Evaluating the quality of life in patients with ulcerative oral lesions

Document Type : Original Article

Authors

1 Assistant Professor, Department of Oral and Maxillofacial Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran

2 MSc Student, Department of Oral and Maxillofacial Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran

3 Department of Oral and Maxillofacial Medicine, School of Dentistry, Yasuj University of Medical Sciences, Yasuj, Iran

4 Assistant Professor, Department of Oral Health and Social Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran

5 Student Research Committee, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran

Abstract

BACKGROUND AND AIM: Oral mucosal lesions can affect patient’s quality of life (QOL). In this evaluation, Persian version of Chronic Oral Mucosal Disease Questionnaire (COMDQ) was used to assess participants’ QOL.
METHODS: This cross-sectional study was done during 2015-2016 in School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran. 95 participants with pemphigus vulgaris (PV), oral recurrent aphthous stomatitis (RAS), and oral lichen planus (OLP) enrolled is this study. The Persian version of COMDQ with 26 questions and 4 domains was used for assessing QOL. The data were analyzed in SPSS software. P-value less than 0.05 was considered significant. Independent t-test, analysis of variance (ANOVA), andTukey's test were used to assess scores of QOL.
RESULTS: The final QOL scores were 45.95 ± 16.31, 53.38 ± 17.64, and 50.02 ± 17.36 for men, women, and all patients, respectively. Patients with OLP and RAS had good QOL, but patients with PV reported lower level of QOL (moderate). None of the COMDQ domains showed significant correlation with gender except pain and functional limitation and overall QOL score.
CONCLUSION: The result of this evaluation revealed a good QOL; considering the type of oral disease, QOL ranged between moderate for patients with PV and good for patients with OLP and RAS.

Keywords


  1. Tabolli S, Bergamo F, Alessandroni L, Di Pietro C, Sampogna F, Abeni D. Quality of life and psychological problems of patients with oral mucosal disease in dermatological practice. Dermatology 2009; 218(4): 314-20.
  2. Scully C, Porter S. Oral mucosal disease: Recurrent aphthous stomatitis. Br J Oral Maxillofac Surg 2008; 46(3): 198-206.
  3. Scully C, Carrozzo M. Oral mucosal disease: Lichen planus. Br J Oral Maxillofac Surg 2008; 46(1): 15-21.
  4. Lavaee F, Majd M. Evaluation of the association between oral lichen planus and hypothyroidism: A retrospective comparative study. J Dent (Shiraz) 2016; 17(1): 38-42.
  5. Khorshidi H, Lavaee F, Ghapanchi J, Golkari A, Kholousi S. The relation of preoperative stress and anxiety on patients' satisfaction after implant placement. Dent Res J (Isfahan) 2017; 14(5): 351-5.
  6. Mumcu G, Inanc N, Ergun T, Ikiz K, Gunes M, Islek U, et al. Oral health related quality of life is affected by disease activity in Behcet's disease. Oral Dis 2006; 12(2): 145-51.
  7. Naito M, Yuasa H, Nomura Y, Nakayama T, Hamajima N, Hanada N. Oral health status and health-related quality of life: A systematic review. J Oral Sci 2006; 48(1): 1-7.
  8. Ni Riordain R, Meaney S, McCreary C. A patient-centered approach to developing a quality-of-life questionnaire for chronic oral mucosal diseases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 111(5): 578-86, 586.
  9. Ni Riordain R, McCreary C. Validity and reliability of a newly developed quality of life questionnaire for patients with chronic oral mucosal diseases. J Oral Pathol Med 2011; 40(8): 604-9.
  10. Ni Riordain R, McCreary C. Further reliability and responsiveness of the Chronic Oral Mucosal Diseases Questionnaire. Oral Dis 2012; 18(1): 60-6.
  11. Okumus O, Kalkan S, Keser G, Pekiner FN. Awareness assessment in Turkish subpopulation with chronic oral mucosal diseases. Eur J Dent 2015; 9(4): 564-72.
  12. Rajan B, Ahmed J, Shenoy N, Denny C, Ongole R, Binnal A. Assessment of quality of life in patients with chronic oral mucosal diseases: A questionnaire-based study. Perm J 2014; 18(1): e123-e127.
  13. Shirzad A, Bijani A, Mehryari M, Motallebnejad M, Mohsenitavakoli S. Validity and reliability of the Persian version of the chronic oral mucosal diseases questionnaire. Caspian J Intern Med 2018; 9(2): 127-33.