Effect of topical phenytoin on creeping attachment of human gingiva: A pilot study

Document Type : Original Article(s)

Authors

1 Department of Periodontics, School of Dental, Kerman University of Medical Sciences, Kerman, Iran

2 Department of Periodontics, School of Dental, Kerman University of Medical Sciences AND Kerman Dental and Oral Diseases Research Center, Kerman, Iran

Abstract

BACKGROUND AND AIM: The aim of this study was to evaluate the effect of topical phenytoin on creeping attachment. METHODS: In this pilot quasi-experimental study, 8 patients referring to Kerman School of Dentistry, Kerman, Iran with Miller class I or II gingival recessions were selected using convenient non-random sampling if they needed root coverage and met the study's inclusion criteria. The patients applied phenytoin mucoadhesive paste 1% on the surface of the deepithelialized gingiva of the tooth with gingival recession, twice a day for two months. Data was analyzed with paired t-test using SPSS version 17. RESULTS: According to our findings, the width of keratinized gingiva at the baseline was 3 mm, and after 2 months it increased to 3.1 mm. The mean baseline height and width of gingival recession were 1.9 mm and 3 mm, respectively, and after 2 months they decreased to 1.8 mm and 2.9 mm accordingly. There was no significant difference in any of the aforementioned parameters before and after treatment (P > 0.05). CONCLUSIONS: The results of this study showed that topical application of phenytoin mucoadhesive paste can not initiate and promote creeping attachment.

Keywords

Journal of Oral Health and Oral Epidemiology
Volume 1, Issue 2 - Serial Number 2
109
December 2012
Pages 65-69

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History

  • Receive Date: 28 January 2013
  • Revise Date: 25 April 2024
  • Accept Date: 12 March 2019

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