Journal of Oral Health and Oral Epidemiology

Journal of Oral Health and Oral Epidemiology

Solitary fibrous tumor of buccal mucosa: A rare entity

Document Type : Case Report(s)

Authors
Sahar Usman 1
Zahid Ali 2
Sana Iqbal 3
Ayesha Aslam 3
Nasir Ud Din 4
1 FCPS Resident, Department of Oral and Maxillofacial Surgery, Abbasi Shaheed Hospital, Karachi, Pakistan
2 Professor, Department of Oral and Maxillofacial Surgery, Abbasi Shaheed Hospital, Karachi, Pakistan
3 MCPS Resident, Department of Oral and Maxillofacial Surgery, Abbasi Shaheed Hospital, Karachi Medical and Dental College, Karachi, Pakistan
4 Associate Professor, Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan
10.22122/johoe.v9i2.1059
Abstract
BACKGROUND AND AIM: Solitary fibrous tumor (SFT) is a quite uncommon tumor that commonly occurs in the pleura but occasionally involves an oral cavity. We are reporting this rare case in the oral cavity. The diagnosis depends on microscopic and immunohistochemical features. Patients with these tumors can be carefully treated with local excision, but tumors with positive margins necessitate close follow-up over several years due to the possible late local recurrence.
CASE REPORT: A 60-year malepatient came in the maxillofacial department in Abbasi Shaheed Hospital, Karachi, Pakistan with swelling for the past 5 years which slowly increased in size with no history of pain. The excisional biopsy was performed under local anesthesia. Histopathological examination showed a well-circumscribed spindle cell tumor with alternating hypo and hypercellular areas with prominent collagenous stroma. Immunohistochemistry (IHC) investigation led to the positive expression of Cluster of Differentiation 34 (CD34) and Signal Transducer and Activator of Transcription-6 (STAT-6) in the spindle cells, and negative expression of Anti-Smooth Muscle Antibody (ASMA). Recurrent or postoperative complications were not observed over some time.
CONCLUSION: SFT in the buccal mucosa of the cheek is a very sporadic condition. It needs to be identified with proper history and clinical examination.
Keywords
fibrous tumor
solitary tumor
neoplasm
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Journal of Oral Health and Oral Epidemiology
Volume 9, Issue 2
Spring 2020
Pages 104-107

  • Receive Date 01 January 2020
  • Revise Date 01 May 2020
  • Accept Date 02 June 2020